We develop advanced capillary electrophoresis (CE) technologies for use in research and development, industry, QC, education and the pharmaceutical market.

Our CE systems offer high performance separation, identification and quantification for size, shape and charged analyses as for entangled polymer solutions, or selected stationary phases commonly used in chromatography. Applications are endless, with PrinCE offering modules and programmable parameters to fit individual needs.

Support materials

A full range of software, buffers, kits and consumables are available for all of our instruments. We also offer comprehensive support documentation for our instruments and buffers, in the form of application notes and leaflets.


The NEXT series is a range of Capillary Electrophoresis analysers expertly designed for for use in research and development, industry, QC, education and the pharmaceutical market

Features
››Allows pressure injection from 96 microwell tray
›› High performance capillary cooling with high air flow speed
›› Full temperature control of sample and buffer during injection and analyses
›› Sufficient capillary compartment space for external remote detector cell
›› Large sample injection volume and duration
›› Ultra short capillary length to external detector
›› Integration with automatic sample handling units (for 96 microwell tray)
›› Next generation dynamic compression injection
technology with unsurpassed injection accuracy

Benefits
›› User configurable multi effective capillary lengths
›› Configurable sample adapters for inserts, vials and 96 microwell tray
›› User replaceable sample and buffer trays
›› Wide selection of on-board and external detectors available
›› Allows high throughput unattended operation
›› Increase analyse time
›› Extremely small bench space
›› Broad application coverage (including environment analyses, forensics, food safety, pharmaceutical and life science)
›› Flexible CE modes of operation: CZE, CGE, MECC/MEKC, IEF, CEC and ITP
›› Broad range of CE accessories and consumables
›› Fast sample and buffer movement
›› On board automated instrument diagnostic functions
›› Regulatory compliance tools

Part No. Model Description
0005.520 /0005.525 PrinCE Next|840
(220/110V)
PrinCE Next CE with temperature controlled inlet autosampler 50/96* sample and 50 buffer positions, temperature controlled capillary compartment, HVPS, outlet vial assembly, detector table, pre-installed PrinCE Next Clarity software, PC and a start-up kit
0005.530/0005.535 PrinCE Next|850
(220/110V)
PrinCE Next CE with temperature controlled inlet autosampler 50/96* sample and 50 buffer positions, outlet autosampler 20 buffer positions, temperature controlled capillary compartment, HVPS, selectable external pressure (up to 10 bars), pre-installed PrinCE Next Clarity software, PC and a start-up kit
0005.550/0005.555 PrinCE Next|870
(220/110V)
PrinCE Next CE with integrated DAD detector 190-610 nm, temperature controlled inlet autosampler 50/96* sample and 50 buffer positions, outlet autosampler 20 buffer positions, temperature controlled capillary compartment, HVPS, selectable external pressure (up to 10 bars), preinstalled PrinCE Next Clarity software, PC and a start-up kit
0005.560/0005.565 PrinCE Next|875
(220/110V)
PrinCE Next CE with integrated DAD detector 190-1010 nm, temperature controlled inlet autosampler 50/96* sample and 50 buffer positions, outlet autosampler 20 buffer positions, temperature controlled capillary compartment, HVPS, selectable external pressure (up to 10 bars), preinstalled PrinCE Next Clarity software, PC and a start-up kit


We’re proud to present the fully automated PrinCE-C 700 series, powerful integrated Capillary Electro-Chromatography systems, which allow the user more hands off time.

Flexible, modular and suitable for almost any application the PrinCE-C 700 couples to any external CE detectors, including UV/VIS, CD, LIF and or MS without the need for any special tools.

Large buffer vials eradicate the need for a replenishment system reducing down-time, making the PrinCE-C 700 systems unique in the CE field.

Flexible:
• Ultra short effective capillary length from 7.2cm
• Outlet end injection
• Sample/buffer cooling to a broad temperature range

Modular:
• Suitable for a broad range of applications including
(R&D, Food, Forensic, Pharmaceutical and Life Science)
• Choice of 2 types of diode array detectors (512 & 1024)

Practical:
• Large sample injection volume
• Dual pressurisation
• Increase analysis time
• Complete temperature control of capillary
• Powerful automated analysis software package
• Unrivaled reproducibility and sample injection

PrinCE-C 700 Series Specifications
Injection Modes
Hydrodynamic injection uses patented Dynamic Compression Injection (DCI) to generate and apply a range of positive and negative pressures with controlled ramping. Electrokinetic injection features controlled ramping in voltage and/or current mode
Duration Up to 650 minutes, 0.01 minutes resolution
Hydrodynamic -180 to 250 mbar, 1mbar resolution
Electrokinetic -30 to +30kV
Modes Current and/or voltage
Ramping Programmable voltage and/or current
Flushing system
Flush range 0 to +2500 mbar, up to 10 bar by external pressure
Features Inlet or outlet and dual pressurisation
Autosampler/fraction collector
User replaceable sample and buffer segments. Automatic randomly optimised choice of positions for inlet and outlet. 30/48 position carousel
Temperature control 4-40°C
Type of vials 300μl inserts, 4ml vials with resealing snap starburst caps including Eppendorf micro
centrifuge tubes
Sample volume Minimum 10μl, maximum 4ml
Buffer volume Maximum 4ml
Capillary compartment
Complete temperature control 5°C below ambient up to 60°C
Capillary
Standard: minimum effective capillary length 8.5cm, minimum total length 30cm
Optional: minimum effective capillary length 7.2cm, minimum total length 30cm
Integrated detector
Real time UV, VIS NIR diode array detector
PrinCE-C 760 190-610nm (512 diodes)
PrinCE-C 770 190-1010nm (1024 diodes)
Wavelength accuracy < 0.3nm
Repetitive accuracy < 0.1nm
Noise level < 3* 10-5AU
Integration time 6ms - 10s
DAx 3D
Powerful CE specific data acquisition and data analysis software package. Peak purity comparing spectrum and the end of a peak, Spectrum library search, identification database, combined peak lists different wavelengths, import and export of data and others
Channels Up to 8 channels
Raw data Simultaneously detects signals, pressure, monitor current, outlet electrode current, oven
temperature, tray temperature and more
Unique features Current and/or voltage controlled method step durations (for on-line pre-concentration). Positive or negative pressure during electrophoresis. Outlet end injections for samples or reagents. Automatic cross-over
Features Programmable time parameters within each step: start time within the step pressure voltage and/or current ramping to set-point + set-point, external events and extended marker programming
Real time display Inlet, outlet, pressure, voltage, current, methods, external events, oven and tray temperature
Power requirements 115/230V, 50/60Hz, 300VA
Dimensions 61×45×48cm
Weight 45kg

PrinCE-C 400:
•Semi-automated, handling up to 40 samples
• Samples and buffer cooling (460 &465)
• Effective capillary length reduced by 5cm
(455 & 465)

PrinCE-C 500:
• Fully automated, handling up to 40 samples
• Second lift for buffer exchange and short end injection
• Samples and buffer cooling (560)

PrinCE-C 600:
• All CE mode capabilities
• Short end injection
• Samples and buffer cooling (660)
• Dual pressurisation

400 Series 500 Series 600 Series
Injection modes
Hydrodynamic injection uses patented Dynamic Compression Injection (DCI) to generate and apply a range of positive and negative pressures with controlled ramping. Electrokinetic injection features controlled ramping in voltage and/or current mode
Duration Up to 650 minutes, 0.01 minutes resolution
Hydrodynamic -180 to 250 mbar, 1mbar resolution
Electrokinetic -30 to +30kV
Modes Current and/or voltage
Ramping Programmable voltage and/or current
Flushing System
Flush Range: 0 to +3000 mbar by DCI device (450 & 460). 0 to +2500 mbar by DCI device, up to 10 bar by external pressure (455 & 465) 0 to +3000 mbar by DCI device 0 to +2500 mbar by DCI device, up to 10 bar by external pressure
Features Inlet and fixed outlet. Inlet or outlet and optional dual pressurisation Inlet or outlet and dual pressurisation
Autosampler/Fractio Collector User replaceable sample and buffer segments. Automatic randomly optimise choice of positions for inlet. 30/48 position carousel User replaceable sample and buffer segments. Automatic randomly optimise choice of positions for inlet and outlet. 30/48 position carousel.
Temperature control 4°C to 40°C (460 & 465) 4°C to 40°C (560) 4°C to 40°C (660)
Type of Vials 300μl inserts, 4ml vials with resealing snap starburst caps including Eppendorf micro centrifuge tubes
Sample Volume Minimum 10μl, maximum 4ml
Buffer Volume Maximum 4ml
Capillary Compartment
Temperature Control 5°C below ambient to 60°C
Capillary Flexible in length and diameter depending on application or configuration
External detector:
Allows the use of any CE- detector including UV/VIS, Fluorescence, Diode Array, LIF, Conductivity, Electrochemical and MS. Prince Technologies’ Detectors: Integrated PrinCE-DAD with 190-610nm (512 Diodes) or 190-1010nm (1024 Diodes), LIF and TraceDec Conductivity.
Software:
WinPrinCE Data Acquisition software. Full control of the Lambda UV-VIS VWL detector. Compatible with any data station. Optional ‘DAx’ powerful Data Acquisition and Analysis software
Channels up to 4
Raw Data Simultaneously detects signals, pressure, monitor current, outlet electrode current, oven
temperature, tray temperature and more
Sophisticated Features Current and/or voltage controlled method step durations (for on-line pre-concentration). Positive or negative pressure during electrophoresis. Outlet end injections for samples or reagents. Automatic cross-over.
Features Programmable time parameters within each step: start time within the step pressure voltage and/ or current ramping to set-point + set-point, external events and extended marker programming
Real time display Inlet, outlet, pressure, voltage, current, methods, external events, oven and tray temperature
Power req. 115/230V, 50/60Hz, 300VA
Dimensions 50×50×54cm
Weight 37kg
Home | Contact Us |Detectors | Application Notes | Software | CE Basics |